• News
  • Health
    • Injury
    • Trauma

Dog Spinal Injury Steroids - Discussing MPSS And PEG

253Shares
13.3KViews

Can dog spinal injury steroids be given for a dog's spinal injury treatment? Are they a good option for a dog's spinal injury? Here are all the details.

Intervertebral disc herniation is one of the most common causes of spinal cord damage in dogs (IVDH). In these situations, compression and contusion together cause spinal cord injury.

One aspect of the injury is successfully relieved by surgical decompression, but medical care for the cumulative injury is still problematic.

X-ray scan of red highlighted area of dog's apinal cord
X-ray scan of red highlighted area of dog's apinal cord

Dog Spinal Injury Steroids Types And Their Uses

COPYRIGHT_SPINE: Published on https://spinal-injury.net/dog-spinal-injury-steroids/ by Dr. Bill Butcher on 2022-09-28T04:10:10.274Z

Methylprednisolone Sodium Succinate (MPSS)

Methylprednisolone sodium succinate (MPSS) is known to work well to stop lipid peroxidation and stop free radicals from being made.

In the National Acute Spinal Cord Injury Studies, or NASCIS trials it was found that starting treatment within 8 hours of the damage was a little bit better.

Even though the results of these trials were initially promising, they are still being debated, and MPSS has not been accepted as a standard of care in human medicine.

Polyethylene Glycol (PEG)

Also praised for its capacity to fuse cell membranes, polyethylene glycol (PEG) has improved outcomes in experimental models of spinal cord injury.

In a clinical trial, PEG was examined in dogs who had IVDH-induced paralysis with absent pain sensibility, the most severe degree of injury.

The results for the dogs in this study were similar to what was found in previous retrospective studies that only used surgery, and they were better than the results for historical controls.

How to handle and care for a dog with IVDD. How to carry, pick up and move a painful dog.

There are several different dosing regimes for MPSS and PEG, both of which are frequently used in veterinary medicine to treat spinal cord injuries. Unfortunately, there are distinctly divergent views on when to administer these medications.

Many neurologists and neurosurgeons, including those in some hospital's neurology and neurosurgery departments, do not employ these medications to treat acute spinal cord injury caused by IVDH.

The main reason why they aren't used is that no placebo-controlled, randomized, blinded trials have ever been done on dogs. This means that no one knows how effective or safe they are.

IVDD Steroids Or NSAIDs (Nonsteroidal Anti-inflammatory Drug)

Corticosteroids work better than NSAIDs for spinal analgesia. NSAIDs don't work when there is "chronic, severe compression of the spinal cord or nerves."

People Also Ask

Do Steroids Help Dogs With IVDD?

Yes. If your dog's mild to severe IVDD injury is discovered early, your veterinarian may attempt to treat it with steroids and anti-inflammatory drugs (to help reduce pain and swelling) along with strict crate rest for around 4 to 6 weeks.

How Do You Treat A Spinal Injury In A Dog?

Dogs with very severe spinal injuries may require surgery. Your vet may need to fuse vertebrae together, pin vertebral bone fragments back into place, or remove part or all of a ruptured disk to take pressure off the nerves in your spine.

Can Dogs Recover From Spinal Injury?

Since spinal cord tissue does not efficiently heal, the effects of an injury may be catastrophic. If the spinal cord is only partially (incompletely) damaged, dogs can make a full recovery because the remaining nerves can take over the function of the lost ones.

Conclusion

The North Carolina State University College of Veterinary Medicine's Dr. Natasha Olby oversaw a multicenter clinical trial to attempt to ascertain whether these dog spinal injury steroids were of any use.

They thought that dogs with a condition called acute thoracolumbar intervertebral disk herniation (TL-IVDH), which causes serious damage to the spinal cord, would do better if polyethylene glycol (PEG) was used instead of MPSS.

The goal of this blinded, randomized, placebo-controlled clinical trial was to find out if PEG and MPSS are safe and effective when used with decompressive surgery.

Share: Twitter | Facebook | Linkedin

About The Authors

Dr. Bill Butcher

Dr. Bill Butcher - With more than two decades of experience, Dr. Bill Butcher aims to provide a repository for educational materials, sources of information, details of forthcoming events, and original articles related to the medical field and about health subjects that matter to you. His goal is to help make your life better, to help you find your way when faced with healthcare decisions, and to help you feel better about your health and that of your family. Bill received his medical degree at Boston University School of Medicine and spent his entire career helping people find the health and medical information, support, and services they need. His mission is to help millions of people feel fantastic by restoring them to optimal health.

Recent Articles

  • Incomplete Quadriplegia - A Bit Of Sensation, A Bit Of Control

    Injury

    Incomplete Quadriplegia - A Bit Of Sensation, A Bit Of Control

    For the condition known as incomplete quadriplegia, the possibility to recover is higher when compared to a complete quadriplegia. It can all depend on the type or the severity of the injury that the spine incurred. Recovery is probable but the journey will be long.

  • Pressure Sore Stages - From Mild Reddening To Damaged Tissues

    Injury

    Pressure Sore Stages - From Mild Reddening To Damaged Tissues

    Having sufficient knowledge of pressure sore stages is important. The wound becomes more serious as each stage develops. Those who are affected need to know what to do for each stage of their pressure sore as it will help them manage their condition.

  • Assistance Dog Tasks - The Wonderful Helper With Four Feet

    Injury

    Assistance Dog Tasks - The Wonderful Helper With Four Feet

    Sometimes, the help wheelchair users can receive are not from people but from animals, specifically from assistance dogs. These well-trained dogs can assist handicapped people with different things. The list of assistance dog tasks is long, and it’s quite comforting to know that certain dogs can aid them live easily.

  • Four Track Skiing - Testing Balance, Leg Strength, And Stability

    Injury

    Four Track Skiing - Testing Balance, Leg Strength, And Stability

    Perhaps for most people, skiing is a wonderful pastime, but for others, it’s a form of physical therapy. People who had stroke, for example, do four track skiing. This activity allows them to work on their muscles and improve their condition.

  • Sexuality And Spinal Cord Injury - Affecting One’s Sexual Function

    Injury

    Sexuality And Spinal Cord Injury - Affecting One’s Sexual Function

    A healthy sex life is part of a healthy relationship. Issues regarding sexuality and spinal cord injury upset couples even if only one of them incurred the said injury. Consulting a doctor is vital to learn about medical ways that offer solutions.

  • Halo Traction - Helping Injured People With Broken Necks

    Injury

    Halo Traction - Helping Injured People With Broken Necks

    For serious neck injuries, a halo traction is advised. It’s also recommended for those born with a curved spine. It helps to stretch and straighten the spine in a gentle manner. Halo traction is also given to those who underwent a spine or neck surgery.

  • Disabled Flying Guide - Never Allow Your Disability To Get In The Way

    Health

    Disabled Flying Guide - Never Allow Your Disability To Get In The Way

    Given their limited mobility, wheelchair users may not be keen on traveling to faraway places. More so if they must get in an airplane just to get to their destination. Knowing some tips from a disabled flying guide will help them deal with it easily.

  • Trauma Resuscitation - Returning Consciousness To Those Near To Death

    Trauma

    Trauma Resuscitation - Returning Consciousness To Those Near To Death

    The early focus of trauma resuscitation in the 18th century were people who drowned. As further studies on lungs widened the scope of the knowledge of doctors regarding this major internal organ, certain progress in the area of resuscitation were achieved. Improvements are still being made up to contemporary times.

  • Incomplete History Of Trauma - From Ancient Egypt To 20th-Century America

    Trauma

    Incomplete History Of Trauma - From Ancient Egypt To 20th-Century America

    Perusing the incomplete history of trauma will initially take one during the ancient times, particularly in Egypt, where an ancient manuscript shed light on how people of long time ago performed surgery. Several advancements were already seen in the early centuries. Further studies were conducted and more medical structures were built in the 19th century and in the 20th century.

  • Injury Severity Score - Determining The Seriousness Of Injuries

  • Tension Pneumothorax - Trouble In The Heart And Lungs

  • Cerebral Perfusion Pressure - Ensuring Blood Flow In The Brain

  • Prehospital Care - When Urgent Medical Attention Saves Lives

  • Pelvic Binder - Managing Pelvic Injuries And Trauma Quickly